Sky is to sell its West London headquarters in a deal worth £545 million.
The broadcaster has instructed BNP Paribas Real Estate to find a buyer for its facility in Osterley that it would then rent back in a projected 30-year agreement.
The site has been home to Sky since its debut as the four-channel service in 1989. It has subsequently grown to become the base for Sky News and Sky Sports.
Sky Studios was opened in 2011 at a cost of £233 million. It is home to eight naturally ventilated studios including five HD studios, 45 edit suites, 14 voice-over suites, four audio suites and on site post-production facilities.
A number of entertainment shows for Sky One are also recorded at the facility.
Estates Gazette, which first reported the news, said Sky was planning to reinvest the cash into its core business, rather than have its finances tied up in a property portfolio.
A sale was previously considered in 2012, but at the time the broadcaster decided against the move.
